Below you will find an up-to-date bibliography of key contributions to intestinal ultrasound research by iUSCAN team members. This reference list is meant to serve as an easy access guide to the latest intestinal ultrasound research in North America.
Clinical Practice
1. Dolinger MT, Kayal M. Intestinal Ultrasound Is the Ideal Patient-Centric, Point-of-Care Tool for Clinical Decision Making in the Inflammatory Bowel Disease Practice. Crohns Colitis 360. 2023;5(3):otad029. doi:10.1093/crocol/otad029
2. Kucharzik T, Tielbeek J, Carter D, et al. ECCO-ESGAR Topical Review on Optimizing Reporting for Cross-Sectional Imaging in Inflammatory Bowel Disease. J Crohns Colitis. 2022;16(4):523-543. doi:10.1093/ecco-jcc/jjab180
3. Lu C, Ma C, Ingram RJM, et al. Innovative Care for Inflammatory Bowel Disease Patients during the COVID-19 Pandemic: Use of Bedside Intestinal Ultrasound to Optimize Management. J Can Assoc Gastroenterol. 2023;6(1):e1-e6. doi:10.1093/jcag/gwac006
4. Mathias H, Rohatinsky N, Murthy SK, et al. The 2023 Impact of Inflammatory Bowel Disease in Canada: Access to and Models of Care. J Can Assoc Gastroenterol. 2023;6(Supplement_2):S111-S121. doi:10.1093/jcag/gwad007
5. Novak K, Tanyingoh D, Petersen F, et al. Clinic-based Point of Care Transabdominal Ultrasound for Monitoring Crohn’s Disease: Impact on Clinical Decision Making. J Crohns Colitis. 2015;9(9):795-801. doi:10.1093/ecco-jcc/jjv105
6. Rohatinsky N, Zelinsky S, Dolinger M, et al. Crohn’s Disease Patient Experiences and Preferences With Disease Monitoring: An International Qualitative Study. Crohns Colitis 360. 2023;5(2):otad012. doi:10.1093/crocol/otad012
7. St-Pierre J, Delisle M, Kheirkhahrahimabadi H, et al. Bedside Intestinal Ultrasound Performed in an Inflammatory Bowel Disease Urgent Assessment Clinic Improves Clinical Decision-Making and Resource Utilization. Crohns Colitis 360. 2023;5(4):otad050. doi:10.1093/crocol/otad050
8. Wright EK, Wang I, Wong D, et al. Accuracy of point‐of‐care intestinal ultrasound for Crohn’s disease. Australas J Ultrasound Med. 2020;23(3):176-182. doi:10.1002/ajum.12218
9. Hudson AS, Huynh HQ, Novak KL, et al. Pediatric Patient and Caregiver Satisfaction With the Use of Transabdominal Bowel Ultrasound in the Assessment of Inflammatory Bowel Diseases. J Pediatr Gastroenterol Nutr. 2023;76(1):33-37. doi:10.1097/MPG.0000000000003618
Diagnosis
10. Novak KL, Jacob D, Kaplan GG, et al. Point of Care Ultrasound Accurately Distinguishes Inflammatory from Noninflammatory Disease in Patients Presenting with Abdominal Pain and Diarrhea. Can J Gastroenterol Hepatol. 2016;2016:4023065. doi:10.1155/2016/4023065
11. Wright EK, Novak KL, Lu C, Panaccione R, Ghosh S, Wilson SR. Transperineal ultrasonography in perianal Crohn disease: A valuable imaging modality. Can J Gastroenterol Hepatol. 2015;29(8):445-447.
12. Novak K, Maaser C, Wilkens R, Maconi G, Kucharzik T, International Bowel Ultrasound Group. Diagnostic accuracy of MRE and ultrasound for Crohn’s disease. Lancet Gastroenterol Hepatol. 2019;4(2):95-96. doi:10.1016/S2468-1253(18)30388-1
Future Directions
11. Wright EK, Novak KL, Lu C, Panaccione R, Ghosh S, Wilson SR. Transperineal ultrasonography in perianal Crohn disease: A valuable imaging modality. Can J Gastroenterol Hepatol. 2015;29(8):445-447.
13. Chavannes M, Kysh L, Allocca M, et al. Role of artificial intelligence in imaging and endoscopy for the diagnosis, monitoring and prognostication of inflammatory bowel disease: a scoping review protocol. BMJ Open Gastroenterol. 2023;10(1):e001182. doi:10.1136/bmjgast-2023-001182
14. Lu C, Gui X, Chen W, Fung T, Novak K, Wilson SR. Ultrasound Shear Wave Elastography and Contrast Enhancement: Effective Biomarkers in Crohn’s Disease Strictures. Inflamm Bowel Dis. 2017;23(3):421-430. doi:10.1097/MIB.0000000000001020
15. Krugliak Cleveland N, Miyatani Y, Picker EA, Rubin DT. At-home Disease Monitoring by Patient-performed Intestinal Ultrasound in Severe Ulcerative Colitis. Inflamm Bowel Dis. 2023;29(12):1997-1998. doi:10.1093/ibd/izad237
16. Lu C, Merrill C, Medellin A, Novak K, Wilson SR. Bowel Ultrasound State of the Art: Grayscale and Doppler Ultrasound, Contrast Enhancement, and Elastography in Crohn Disease. J Ultrasound Med Off J Am Inst Ultrasound Med. 2019;38(2):271-288. doi:10.1002/jum.14920
General Reviews
17. Dolinger MT, Kayal M. Intestinal ultrasound as a non-invasive tool to monitor inflammatory bowel disease activity and guide clinical decision making. World J Gastroenterol. 2023;29(15):2272-2282. doi:10.3748/wjg.v29.i15.2272
18. Cleveland NK, Picker EA, Dolinger MT, Rubin DT. The Arrival of Intestinal Ultrasound for Inflammatory Bowel Disease Care in the United States. Gastroenterol Hepatol. 2023;19(3):147-154.
19. Dolinger MT, Calabrese E, Pizzolante F, Abreu MT. Current and Novel Uses of Intestinal Ultrasound in Inflammatory Bowel Disease. Gastroenterol Hepatol. 2023;19(8):447-457.
20. Dolinger MT, Kellar A. Point-of-Care Intestinal Ultrasound in Pediatric Inflammatory Bowel Disease. Curr Gastroenterol Rep. 2023;25(11):355-361. doi:10.1007/s11894-023-00892-7
21. Krugliak Cleveland N, St-Pierre J, Kellar A, Rubin DT. Clinical Application of Intestinal Ultrasound in Inflammatory Bowel Disease. Curr Gastroenterol Rep. 2024;26(2):31-40. doi:10.1007/s11894-024-00915-x
Guidelines
22. Chavannes M, Dolinger MT, Cohen-Mekelburg S, Abraham B. AGA Clinical Practice Update on the Role of Intestinal Ultrasound in Inflammatory Bowel Disease: Commentary. Clin Gastroenterol Hepatol. 2024;22(9):1790-1795.e1. doi:10.1016/j.cgh.2024.04.039
23. Dolinger MT, Krugliak Cleveland N, Rubin DT, Dubinsky MC. Guide to Intestinal Ultrasound Credentialing, Documentation, and Billing for Gastroenterologists in the United States. Am J Gastroenterol. 2023;118(9):1528-1531. doi:10.14309/ajg.0000000000002253
Pediatrics
24. Kellar A, Dolinger M, Novak KL, Chavannes M, Dubinsky M, Huynh H. Intestinal Ultrasound for the Pediatric Gastroenterologist: A Guide for Inflammatory Bowel Disease Monitoring in Children: Expert Consensus on Behalf of the International Bowel Ultrasound Group (IBUS) Pediatric Committee. J Pediatr Gastroenterol Nutr. 2023;76(2):142-148. doi:10.1097/MPG.0000000000003649
25. Dolinger MT, Choi JJ, Phan BL, Rosenberg HK, Rowland J, Dubinsky MC. Use of Small Bowel Ultrasound to Predict Response to Infliximab Induction in Pediatric Crohn’s Disease. J Clin Gastroenterol. 2021;55(5):429-432. doi:10.1097/MCG.0000000000001367
26. Dolinger MT. The Role of Noninvasive Surrogates of Inflammation in Monitoring Pediatric Inflammatory Bowel Diseases: The Old and the New. Gastroenterol Clin North Am. 2023;52(3):497-515. doi:10.1016/j.gtc.2023.05.003
27. Dolinger MT, Aronskyy I, Kellar A, Spencer E, Pittman N, Dubinsky MC. Early Intestinal Ultrasound Response to Biologic Therapy Predicts Endoscopic Remission in Children with Ileal Crohn’s Disease: Results from the Prospective Super Sonic Study. J Crohns Colitis. 2024;18(7):1002-1011. doi:10.1093/ecco-jcc/jjad216
28. Kellar A, Wilson S, Kaplan G, DeBruyn J, Tanyingoh D, Novak KL. The Simple Pediatric Activity Ultrasound Score (SPAUSS) for the Accurate Detection of Pediatric Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2019;69(1):e1-e6. doi:10.1097/MPG.0000000000002298
Pregnancy
29. Gottlieb ZS, Dolinger M, Kayal M, et al. Clinical Challenge: Proactive Precise Management of Active Ulcerative Colitis During Pregnancy-Advantages of Point-of-Care Intestinal Ultrasound and Therapeutic Drug Monitoring. Dig Dis Sci. 2022;67(8):3557-3561. doi:10.1007/s10620-022-07532-6
Scoring Systems
28. Kellar A, Wilson S, Kaplan G, DeBruyn J, Tanyingoh D, Novak KL. The Simple Pediatric Activity Ultrasound Score (SPAUSS) for the Accurate Detection of Pediatric Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2019;69(1):e1-e6. doi:10.1097/MPG.0000000000002298
30. Goodsall TM, Jairath V, Feagan BG, et al. Standardisation of intestinal ultrasound scoring in clinical trials for luminal Crohn’s disease. Aliment Pharmacol Ther. 2021;53(8):873-886. doi:10.1111/apt.16288
31. Kucharzik T, Maaser C, Novak K. Are we ready to use activity scores for intestinal ultrasound in ulcerative colitis? United Eur Gastroenterol J. 2021;9(4):423-424. doi:10.1002/ueg2.12077
32. Novak KL, Nylund K, Maaser C, et al. Expert Consensus on Optimal Acquisition and Development of the International Bowel Ultrasound Segmental Activity Score [IBUS-SAS]: A Reliability and Inter-rater Variability Study on Intestinal Ultrasonography in Crohn’s Disease. J Crohns Colitis. 2021;15(4):609-616. doi:10.1093/ecco-jcc/jjaa216
33. Delisle M, Wilkens R, Novak KL. Keeping It Simple: Using Intestinal Ultrasound to Assess Ulcerative Colitis with a Novel UC-Ultrasound Index. J Crohns Colitis. 2021;15(8):1250-1252. doi:10.1093/ecco-jcc/jjab066
34. Dolinger MT, Aronskyy I, Kellar A, et al. Determining the Accuracy of Intestinal Ultrasound Scores as a Prescreening Tool in Crohn’s Disease Clinical Trials. Am J Gastroenterol. 2024;119(5):930-936. doi:10.14309/ajg.0000000000002632
35. Novak KL, Kaplan GG, Panaccione R, et al. A Simple Ultrasound Score for the Accurate Detection of Inflammatory Activity in Crohn’s Disease. Inflamm Bowel Dis. 2017;23(11):2001-2010. doi:10.1097/MIB.0000000000001174
Strictures
36. Lu C, Rosentreter R, Delisle M, et al. Systematic review: Defining, diagnosing and monitoring small bowel strictures in Crohn’s disease on intestinal ultrasound. Aliment Pharmacol Ther. 2024;59(8):928-940. doi:10.1111/apt.17918
Training
21. Krugliak Cleveland N, St-Pierre J, Kellar A, Rubin DT. Clinical Application of Intestinal Ultrasound in Inflammatory Bowel Disease. Curr Gastroenterol Rep. 2024;26(2):31-40. doi:10.1007/s11894-024-00915-x
37. Madsen GR, Wilkens R, Boysen T, et al. The knowledge and skills needed to perform intestinal ultrasound for inflammatory bowel diseases—an international Delphi consensus survey. Aliment Pharmacol Ther. 2022;56(2):263-270. doi:10.1111/apt.16950
38. Madsen GR, Tolsgaard MG, Gecse K, et al. Classifying Inflammation on Intestinal Ultrasound Images and Cineloops - A Learning Curve Study. J Crohns Colitis. Published online July 19, 2024:jjae112. doi:10.1093/ecco-jcc/jjae112
Treatment Response
5. Novak K, Tanyingoh D, Petersen F, et al. Clinic-based Point of Care Transabdominal Ultrasound for Monitoring Crohn’s Disease: Impact on Clinical Decision Making. J Crohns Colitis. 2015;9(9):795-801. doi:10.1093/ecco-jcc/jjv105
22. Chavannes M, Dolinger MT, Cohen-Mekelburg S, Abraham B. AGA Clinical Practice Update on the Role of Intestinal Ultrasound in Inflammatory Bowel Disease: Commentary. Clin Gastroenterol Hepatol. 2024;22(9):1790-1795.e1. doi:10.1016/j.cgh.2024.04.039
39. Al-Ani AH, Vaughan R, Christensen B, Bryant RV, Novak KL. Treat to transmural healing: how to incorporate intestinal ultrasound into the treatment of inflammatory bowel disease. Br J Radiol. 2022;95(1137):20211174. doi:10.1259/bjr.20211174
40. Ilvemark JFKF, Hansen T, Goodsall TM, et al. Defining Transabdominal Intestinal Ultrasound Treatment Response and Remission in Inflammatory Bowel Disease: Systematic Review and Expert Consensus Statement. J Crohns Colitis. 2022;16(4):554-580. doi:10.1093/ecco-jcc/jjab173
41. Spencer EA, Bergstein S, Dolinger M, et al. Single-center Experience With Upadacitinib for Adolescents With Refractory Inflammatory Bowel Disease. Inflamm Bowel Dis. Published online December 22, 2023:izad300. doi:10.1093/ibd/izad300
42. Wilkens R, Dolinger M, Burisch J, Maaser C. Point-of-Care Testing and Home Testing: Pragmatic Considerations for Widespread Incorporation of Stool Tests, Serum Tests, and Intestinal Ultrasound. Gastroenterology. 2022;162(5):1476-1492. doi:10.1053/j.gastro.2021.10.052
43. Zorzi F, Rubin DT, Cleveland NK, Monteleone G, Calabrese E. Ultrasonographic Transmural Healing in Crohn’s Disease. Am J Gastroenterol. 2023;118(6):961-969. doi:10.14309/ajg.0000000000002265
